MT-2 (10 MG X 10 VIALS)

MT-2

Melanotan-2

Description

MT-2 (or Melanotan II) is another synthetic peptide of hormones nature and

lactam cyclic analog of melanocortin protein hormone alpha-melanocyte

stimulating hormone; its molecular weight/mass is 1024.2 with molecular

formula is C50H69N15O9. This analog has typical features of proteins.

MT-2 is a sterile, non-pyrogenic, white lyophilized powder intended for

subcutaneous or intramuscular injection, after reconstitution with sterile

Water for Injection.

Mechanism of Action

MT-II contributes to satiety via a hypothalamic signal. MT-II also affects

skin pigmentation as it is a melanocyte-stimulating hormone (MSH). MT-II

binds to melanocortin receptors and affects the MC4R activity

demonstrating an effect on meal size and choice but not meal frequency.

In a pilot study using human subjects, a significant change in skin

pigmentation (darkening) occurred after just 5 injections of MT-II used

every other day. This same study also noted that males that used MT-II

experienced penile erections concomitantly with “stretching and yawning.”

Between one and five hours after injection of MT-II. Another study found 8

of 10 men increase erectile rigidity to 38 minutes verses 3 minutes with

placebo. The only noted side effects were mild nausea, decreased appetite,

and “stretching and yawning.”.

Another potential benefit of MT-II is its affects on food choice, intake, and

nutrient partitioning. Banno’s study surmised that food intake and body

weight were decreased by chronic administration of MT-II. Insulin

sensitivity as well as glucose tolerance was improved by MT-II. Serum

triglyceride levels were also decreased by MT-II, and the affects persisted

for at least 25 days. Thus one can conclude MT-II could be used to treat

obesity, metabolic syndrome, and any co morbid disorders.

Adverse reactions

• Nausea
• Facial Flushing
• Fatigue
• Vomiting
• Injection site reactions
• Zero incidence of erections
• No change in vital signs or haematological parameters, blood biochemistry

(liver and renal function)

Instructions for reconstitution

Flip off the top of the peptide vial with your thumb. Use the alcohol swab to wipe the

rubber stopper of the peptide vial. Push the needle of the syringe into the middle of the

rubber stopper so it goes through the rubber and into the vial. Now, while angling the

needle so that the water for injection goes down the side of the glass, rather than

directly into the powder, inject the water for injection into the vial. Repeat this step until

you have the correct amount of water in the vial. The powder will dissolve quickly,

however it can help to gently roll the vial in between your fingers (do not shake the vial

vigorously). Remove the syringe and dispose of it. You should never re-use a syringe.

Dosage

Recommended dosage of MT-2:

•  0.25 – 1.5 mg once per day.

Storage

• After reconstitution, may be stored for a maximum of 14 days in a refrigirator at 2°C — 8°C.
• Store vials in an upright position.
• Store in a refrigerator (2°C — 8°C). Keep in the outer carton in order to protect from light.
• For one month can be stored at room temperature.